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br Marginal zone lymphoma Marginal zone lymphoma MZL compris
2021-04-12
Marginal zone lymphoma Marginal zone lymphoma (MZL) comprises three lymphoma entities that arise from the marginal zone surrounding the germinal center: extranodal MZL or mucosa-associated lymphoid tissue (MALT), splenic MZL, and nodal MZL. Deep sequencing of nodal MZL patients found that 5/35 (1
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dihydroxycholesterol OHC was recently identified by classic
2021-04-12
7α,25-dihydroxycholesterol (7α,25-OHC) was recently identified by classic analytical methods as a high-affinity ligand for EBI2 (Hannedouche et al., 2011; Liu et al., 2011). 7α,25-OHC was previously identified as an intermediate in the alternate pathway of hepatic bile BQ-123 synthesis (Russell, 200
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Homologous recombination HR has important roles in the repai
2021-04-12
Homologous recombination (HR) has important roles in the repair of stalled or collapsed DNA replication forks, as well as of DNA double-strand breaks. Among the factors required for HR in human oxidative phosphorylation are RAD51, BRCA1, and BRCA2 (Davies et al., 2001, Sung and Klein, 2006, Xia et
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ikk inhibitor The archaea are a group of
2021-04-12
The archaea are a group of microorganisms, and many belong to extremophiles, living in extreme environments, such as those with high temperatures [6], [7]. Methanocaldococcus jannaschii is a methane-producing archaea [8]. It grows at pressures of up to more than 200atm and at an optimum temperature
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In conclusion as illustrated in Fig G in response to
2021-04-12
In conclusion, as illustrated in Fig. 5G, in response to MNNG-induced DNA damage, PARP-1 appears to have dual roles in determining the cell fate in response to MNNG: PARP-1 activation is the cause of non-apoptotic cell death via ATP depletion and PARP-1 activation is able to elicit a self-protective
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To compare glucose metabolism via oxidative phosphorylation
2021-04-12
To compare glucose metabolism via oxidative phosphorylation to that via glycolysis, a bioenergetics plot was constructed (Fig. 3A). In most cells, a decrease in one bioenergetics pathway is compensated by an increase in the other. However, following NAT1 deletion, there was a decrease in both oxida
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br The contribution of Interference RNA and
2021-04-12
The contribution of Interference RNA and epigenetic in OA attenuation Interference RNA, a cellular mechanism for post-transcriptional gene silencing that is associated with mRNA. The potential of RNAi has successfully silenced the wide range of protein coding genes. Its high specificity sanctions
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br Materials and methods br
2021-04-12
Materials and methods Results Discussion Our study assessed the cytokine and chemokine changes associated with first onset PP as compared to HP and HNP groups. In the monocytes/ macrophages/ dendritic Mupirocin panel, IL-6 levels were found to be significantly elevated in both HP and PP gr
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Recent pharmaceutical research in the field of respiratory d
2021-04-12
Recent pharmaceutical research in the field of respiratory diseases has sought to make available new agents that specifically and selectively antagonize the actions of cysteinyl–leukotrienes. Such an effort has resulted in the development of two classes of drugs, effective in counteracting Cys-LTs p
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Compounds were prepared via the routes shown
2021-04-12
Compounds were prepared via the routes shown in , varying the sequence of reactions to install the thiazole or the phenyl ring at the end of the synthesis (pyridyl examples were prepared using similar chemistry). The aminothiazole building blocks were prepared as shown in . 5-Aminothiazole was prep
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Fmoc-D-Phe(4-Cl)-OH br Introduction The dorsal periaqueducta
2021-04-12
Introduction The dorsal periaqueductal gray matter (dPAG) is a midbrain site markedly involved in fear/anxiety-evoked responses as well as in nociception (see, for example, Bandler and Carrive, 1988, Deakin and Graeff, 1991, Fardin et al., 1984a, Fardin et al., 1984b, Litvin et al., 2007). Chemic
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The co localization of CRF and CCK has been investigated
2021-04-12
The co-localization of CRF and CCK has been investigated in extensive studies. Sutin and Jacobowitz (1988) examined the immunocytochemical localization of peptides and neurochemicals in the rat laterodorsal tegmental nucleus and found the existence of CRF, atrial natriuretic factor (ANF), neurotensi
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Fmoc-Phe-OH Accurate equilibrium predictions of CO containin
2021-04-12
Accurate equilibrium predictions of CO2 containing mixtures, however, are challenging with traditional equations of state. The reason for this may be that CO2 has a large quadrupole moment. The large quadrupole moment of CO2, as well as size asymmetry, are for instance believed to be the reasons for
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Quantum walks can be connected to extended CMV matrices as
2021-04-12
Quantum walks can be connected to extended CMV matrices as follows. If all Verblunsky coefficients with even index vanish, then the extended CMV matrix becomes which resembles the matrix representation U. One may notice, however, that in the extended CMV matrix , whereas in the quantum walk matri
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Acknowledgments br Introduction Steroidogenesis the
2021-04-10
Acknowledgments Introduction Steroidogenesis, the process of testosterone synthesis, occurs in the adrenal cortex, testis and ovary, and it is controlled by luteinizing hormone (LH), which is synthesized and secreted from the pituitary (Hanukoglu, 1992, Payne and Youngblood, 1995). In the testis
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