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br Introduction Natural antioxidants in
2024-09-24
Introduction Natural antioxidants, in vegetables, have gained the attention of both researchers and consumers. Vegetable amaranth (Amaranthus tricolor) is a good source of minerals, vitamins, phenolics, and carotenoids; it also contains betalains, a nitrogen containing group of natural pigments,
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It is noteworthy that in both cases there is
2024-09-24
It is noteworthy that in both cases there is a higher risk for prematurity [44], [61], [97], [98] and for deliveries of newborn small for GA [89], [95], [97], [98]. sFlt-1:PlGF has been showed to be inversely correlated with GA at birth, since 86% of pregnant women who gave birth at Higher Discovery
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It is reported that Adiponectin is able to
2024-09-23
It is reported that Adiponectin is able to suppress NF-κB pathway, and Bcr-Abl fusion oncoprotein in CML activates NF-κB by stimulating its nuclear translocation and also by enhancing its transactivation function [25], [26]. Therefore, it is tempting to hypothesize that NF-κB pathway might be involv
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Given the profound expression of HT A and HT A
2024-09-23
Given the profound KP372-1 synthesis of 5-HT1A and 5-HT2A in the hippocampal CA1 region, and their potential to complex with mGluRs, the objective of this study was to examine if sleep deprivation alters the expression of 5-HT1A and 5-HT2A receptors and determine whether potential changes are rever
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The most widely recognized effects of adenosine are operated
2024-09-23
The most widely recognized effects of adenosine are operated through inhibiting A1R, one of the most abundant G protein-coupled receptors in NCT-502 mg tissue [53]. A1R are located presynaptically, postsynaptically and nonsynaptically [54]. Effect of adenosine in neuronal circuits of adult mammals i
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The following are the supplementary data related
2024-09-23
The following are the supplementary data related to this article. Conflict of interest Acknowledgements Disclosure of interest Introduction Since the introduction of platinum-based chemotherapy, metastatic testicular cancer has become a curable disease and most testicular cancer patien
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br Materials and methods br Results br Discussion We have
2024-09-23
Materials and methods Results Discussion We have developed a high-throughput functional genomic screen that allows the identification of genes that confer drug resistance. Several factors have been identified which must be taken into account to develop a reliable screen. In particular, cons
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P 22077 Among the most important Ca regulatory mechanisms
2024-09-23
Among the most important Ca regulatory mechanisms are the Plasma Membrane Calcium ATPase (PMCA) and Sarcoplasmic Reticulum Calcium ATPase (SERCA). These pumps belong to the family of P-ATPases, which share the formation of an acid-stable phosphorylated intermediate as part of their reaction cycle. P
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Despite these conflicting data about COX ER
2024-09-23
Despite these conflicting data about COX-2/ER correlations, a large body of evidence supports that elevated COX-2 expression in breast cancer is a constant feature of high stage disease and a predictor of worse outcome. Upregulation of COX-2 protein has been identified in approximately 40% of cases
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Senegenin Thus a majority of known chemical and
2024-09-23
Thus, a majority of known chemical and physico-chemical methods of metallic ions assay has a number of disadvantages, such as a low sensitivity and selectivity, high costs and complexity of the equipment. Therefore, the development of simple cost-effective sensitive methods of quantitative analysis
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Among steroid saponins ginsenosides are the active
2024-09-23
Among steroid saponins, ginsenosides are the active components of ginseng, a well-known chinese medicinal plant. More than hundreds of different ginsenosides have been isolated from ginseng and have shown in the past to be membrane active substances and to influence the membrane by modulating lipid
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br Concluding remarks br Conflict of interest br
2024-09-21
Concluding remarks Conflict of interest Acknowledgment This work was supported by the H.E.B. Endowed Chair in Marine Science (to P.T.) and University of Texas Marine Science Institute endowment-supported scholarships (to A.C). Introduction Disorders of sex development (DSD) are defined
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br Serine glycine and one
2024-09-21
Serine/glycine and one-carbon metabolism Altered serine metabolism in tumors was noted nearly half a century ago, and elevated flux through the de novo serine synthesis pathway (SSP) is a common phenomenon in cancer fexofenadine hydrochloride [43]. The SSP branches from glycolysis at the point o
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At the organismal level skeletal
2024-09-21
At the organismal level, skeletal muscle, lung and adipose tissues mediate net de novo synthesis and release of glutamine, whereas net glutamine catabolism occurs in the kidney [7]. The liver exhibits net glutamine consumption coupled to urea production in the post-absorptive state, and net glutamin
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neomycin concentration for cell selection ALK fusion positiv
2024-09-21
ALK fusion-positive NSCLC is clinically actionable because it can be targeted by several FDA-approved drugs, including the first generation TKI crizotinib, which is a dual inhibitor to MET and ALK [15], and the second generation inhibitors, alectinib and ceritinib, both of which are highly-selective
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